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What is Wharton’s Jelly?

July 21, 2025

Deep within the umbilical cord lies a remarkable substance known as Wharton’s Jelly. Soft yet durable, this gelatinous tissue naturally protects the cord’s blood vessels throughout pregnancy. Beyond its cushioning properties, it holds a rich concentration of regenerative compounds like collagen, hyaluronic acid, chondroitin sulfate, and immune-signaling factors that help drive tissue healing.

At the heart of Wharton’s Jelly are MSCs—medicinal signaling cells. Formerly called mesenchymal stem cells, these potent cells have the unique ability to signal the body to repair damaged tissues, reduce inflammation, and promote overall healing.

How is Wharton’s Jelly Sourced and Processed?

Unlike some sources of stem cells, Wharton’s Jelly is collected ethically and responsibly. It is derived from the umbilical cords of healthy, full-term babies who go home safely with their parents. This ensures there are no ethical dilemmas or harm involved in collection.

Once obtained, specialized labs purify and rigorously test these tissues to ensure safety and quality. For instance, labs may screen for viral particles, even testing for elements like COVID-19 spike proteins to ensure only the highest-quality products are used. These refined preparations can then be used in regenerative therapies, offering patients a safe and controlled option for supporting healing.

Why Consider Wharton’s Jelly for Regenerative Therapy?

Regenerative medicine focuses on helping the body repair itself by leveraging its own biological signaling systems. Wharton’s Jelly-derived products are a cornerstone of these therapies, particularly for joint health and musculoskeletal conditions.

Compared to using a patient’s own older cells—harvested from fat or bone marrow, which have been exposed to decades of environmental toxins—Wharton’s Jelly provides a younger, more potent source of regenerative compounds. This approach avoids creating additional inflammation at harvest sites and reduces the risk of cells being attracted to the wrong area of inflammation.

At Nourish House Calls, we incorporate advanced regenerative solutions such as stem cell therapy using Wharton’s Jelly-derived products. These treatments are especially effective in addressing joint-related concerns, helping reduce inflammation, stimulate tissue repair, and often delay or even avoid surgery.

How Does Nourish House Calls Optimize Regenerative Treatments?

Any regenerative therapy works best when the body’s environment is healthy. Simply injecting regenerative products into an area without considering systemic health is like throwing grass seed onto concrete—it’s unlikely to thrive.

Our approach combines regenerative and longevity medicine with functional medicine principles. This includes optimizing hormones, reducing systemic inflammation, ensuring a healthy diet, supporting detoxification, and improving sleep, exercise, and sunlight exposure.

In this optimal “soil,” regenerative products have their best chance to deliver meaningful, lasting results. It also ensures that the investment you’re making in regenerative care is as effective as possible.

Who May Benefit from Wharton’s Jelly Injections?

Wharton’s Jelly-derived regenerative injections can support healing in a range of musculoskeletal conditions, including:

  • Joint degeneration or osteoarthritis
  • Meniscal or labral tears (when not fully torn)
  • Mild to moderate cartilage loss
  • Ligament and tendon injuries (partial tears)
  • Chronic inflammatory conditions in joints

While regenerative therapies hold great promise, they’re not always a substitute for surgery in cases of severe damage. However, they may help patients avoid or delay invasive procedures and promote improved function and pain relief in many cases.

Video Overview

Watch Joya Van Der Laan, MSN, FNP-BC, explain the science and safety of regenerative medicine using Wharton’s Jelly:

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If you’re interested in learning whether regenerative medicine is right for you, we invite you to schedule a complimentary 15-minute discovery call. It’s a no-pressure opportunity to discuss your goals, ask questions, and better understand your treatment options.

We’re committed to providing compassionate, personalized care—whether in-office, at-home, or through convenient telehealth visits.

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Frequently Asked Questions

What is Wharton’s Jelly made of?

Wharton’s Jelly is a gelatinous tissue in the umbilical cord containing collagen, hyaluronic acid, chondroitin sulfate, and medicinal signaling cells (MSCs). These components help protect and cushion blood vessels during pregnancy and have powerful regenerative properties when used therapeutically.

Is Wharton’s Jelly ethically sourced?

Yes. The tissue is collected only from full-term babies delivered safely, who go home with their parents. There is no harm or ethical dilemma in collecting the umbilical cords after birth. Labs then purify and test the tissue to ensure its safety.

How does Wharton’s Jelly promote healing?

The MSCs and bioactive compounds in Wharton’s Jelly help reduce inflammation and signal the body to repair damaged tissues. This promotes regeneration in joints, ligaments, tendons, and other musculoskeletal structures, supporting pain relief and improved function.

Why use Wharton’s Jelly instead of my own stem cells?

While using a patient’s own cells is possible, those cells are older and may have been exposed to more toxins over time. Harvesting them also creates new sites of inflammation that can reduce the precision of treatment. Wharton’s Jelly provides a younger, more potent, and ethically sourced alternative.

What conditions are best suited for Wharton’s Jelly injections?

These therapies are especially helpful for joint-related issues such as osteoarthritis, meniscal or labral tears, cartilage degeneration, and certain ligament or tendon injuries. While severe tears may still require surgery, regenerative therapy can help many patients avoid or delay more invasive procedures.

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